The author describes in the article the possibilities of using the database of prisoners of the Terezín ghetto for business history research. He describes the development of the database of the Terezín Initiative Institute, which not only enables statistical analysis of survival of prisoners – entrepreneurs in diffi cult conditions of Terezín ghetto and subsequent transports to the east, but also shows how can be the database used to study First Republic Jewish entrepreneurs. A comparison of this database with a list of important Jewish entrepreneurs of the First Republic showed that up to 85 % of them could have emigrated.